North Lab Members
Jenna Frame, Ph.D. (Postdoctoral Fellow)
Jenna earned her B.S., M.S., and Ph.D. degrees at the University of Rochester, New York. Under the mentorship of Dr. James Palis, she studied the development of the first erythroid lineages and emergence of erythro-myeloid progenitors in the murine embryo. Jenna joined the North lab in January 2016, and is interested in translating her knowledge of the hematopoietic system to interrogate the influence of metabolic status and inflammation in the regulation of HSC production and function in zebrafish. Jenna is currently supported by a NIH-funded T32 training grant through the BIDMC Center for Vascular Biology. Outside of the laboratory, Jenna enjoys spending time with family, playing tennis and the piano, and trying new restaurants.
Wade Sugden, Ph.D. (Postdoctoral Fellow)
Wade grew up in Idaho, and got his hands wet with zebrafish during his Bachelor’s studies at the University of Oregon, where he learned about zebrafish craniofacial development and molecular biology techniques in the lab of Dr. Charles Kimmel. He did his graduate studies in the lab of Dr. Arndt F. Siekmann at the Max Planck Institute for Molecular Biomedicine in Germany, focusing on hemodynamic control of vascular patterning during embryonic development. Wade finished his Ph.D. degree in February, 2017 and joined the North Lab in December, 2017 and is interested in the intersection of mechanical forces and genetic control of HSC specification, expansion and differentiation. When not in the lab he enjoys running, hiking and traveling.
Eleanor Meader, Ph.D. (Postdoctoral Fellow)
Ellie is a postdoctoral fellow studying the role of oxygen and glucose metabolism in hematopoietic development. She joined the North lab after completing her PhD project on the role of micro-RNAs in the differentiation of hematopoietic progenitors from human pluripotent cells at the Lako lab at Newcastle University. Ellie’ spends her free time rock-climbing, baking and hiking.
Ashlee Conway, PhD (Postdoctoral Fellow)
Ashlee joined the North Lab in June 2018, after completing her PhD at the Royal Alfred Hospital in Melbourne, Australia. Her doctoral and postdoctoral studies have focused on mammalian erythropoiesis, the molecular biology of the red blood cell, and the modeling of congenital blood disorders in mice and in vitro. She also has a passion for education and spent her doctoral years tutoring Immunology and lecturing on Globinopathies for undergraduate students. Outside of the laboratory, Ashlee writes fiction and received an ‘Awesome Indie Award’ in 2017 for a sci-fi novel she released with an Australian publisher.
Mariam Hachimi, Ph.D. (Postdoctoral Fellow)
Mariam Hachimi has a PhD degree in Molecular Biology from the Autonomous University of Madrid. Mariam joined the North lab in October 2018 as a postdoctoral fellow. She is interested in the role of anti-inflammatory signals on HSC emergence, as well as determining the mechanism of action of these stimuli in HSC maintenance. Mariam loves meeting new people every day, and discovering new food and traveling experiences everywhere.
Lindsay is a graduate student in the Biological and Biomedical Sciences program at Harvard Medical School. She is also completing a paracurricular certificate in Therapeutic Sciences through the Harvard Therapeutics Graduate Program. Originally from the Hudson Valley, New York, she earned her undergraduate degree in Biological Sciences with a concentration in Molecular and Cell Biology at Cornell University. Lindsay's research is focused on the role of inflammation in regulating hematopoietic stem cell specification and maturation, and is funded by an NIH F31 Fellowship from the National Heart, Lung and Blood Institute. When not in the lab, Lindsay can usually be found running, baking, and/or watching the Red Sox.
Rebecca is a graduate student in the Biological and Biomedical Sciences program at Harvard Medical School. Rebecca is originally from El Paso, TX, and earned her undergraduate degree in Biochemistry from the University of Texas at El Paso. Rebecca’s research is focused on epigenetic regulation governing hematopoietic stem cell specification and function. When not in the lab, Rebecca enjoys watching The Bachelor and drinking frozen strawberry margaritas.
TECHNICIANS AND UNDERGRADUATES
Gisele Bailey (Undergraduate Student)
Gisele is an undergraduate student at Harvard College concentrating in Human Developmental and Regenerative Biology (HDRB). Gisele joined the North lab in the fall of 2016 to conduct research for her thesis paper. She is currently studying possible synergistic effects of PGE2 and Vitamin D on hematopoietic stem cell proliferation. In her free time she enjoys being a member of Harvard women's basketball team, exploring Boston, and listening to music.
Nadine Budrow (Zebrafish Facility Manager)
Nadine received her Bachelors of Science from Salem State University in 2015. She studied biology and chemistry with a focus on marine life. While working towards her degree she worked part time as a lab technician in the fish facilities at Boston Children's Hospital. One year upon graduation she was hired full time as the fish facility coordinator for Beth Israel Deaconess Medical Center.
Tim Long (Research Technician)
Tim graduated from Bowdoin College in 2017 with a B.A. in Biochemistry, with honors, and a minor in Mathematics. At Bowdoin, he studied the interactions between the retinoic acid, hedgehog, and ectodysplasin cell signaling pathways during early zebrafish tooth development. In the North Lab, he assists Jenna with her research, handles supply and equipment orders for the lab, and helps with the care and maintenance of the fish facility. Outside of the lab, Tim likes to spend his time swimming, hiking, playing tabletop and video games, and listening to vinyl records!